Laboratory of Biochemical and Biotechnological Processes

Aristotle University of Thessaloniki

Publications

Since 2020, the Laboratory of Biochemical and Biotechnological Processes has a total of 17 publications in international journals, 3 participations in European or global research and innovation projects and 5 participations in National and regional co-funded research and innovation projects.

Journal Publications

  1. “Extending the green stage of Haematococcus pluvialis as a crucial precursor for efficient astaxanthin production: Optimization via Taguchi design”, Samara C., Biziouras A., Papapanagiotou G., Chatzidoukas C., Biochemical Engineering Journal 220, 2025 (https://doi.org/10.1016/j.bej.2025.109763)
  2. “Microalgae Bioprospecting for the Food Industry: Insights into the Autotrophic Biomass Production and Macromolecular Accumulation of Four Microalgal Species”, Papapanagiotou G., Samara C., Psachoulia P., Chatzidoukas C., World Journal of Microbiology and Biotechnology 41(12), 2025 (org/10.1007/s11274-024-04229-y).
  3. “Impact of Chlorella sorokiniana feed additive on poultry growth health and oxidative stress in erythrocytes”, Tsamesidis I., Pappa A., Charisis A., Prentza Z., Theocharis K., Patsias A., Foukas D., Chatzidoukas C., Kalogianni E.P., Scientific Reports, 14(1), 31588, 2024 (org/10.1038/s41598-024-76998-3).
  4. “Linking Cultivation Conditions to the Fatty Acid Profile and Nutritional Value of Chlorella sorokiniana Lipids”, Papapanagiotou G., Charisis A., Samara C., Kalogianni E.P., Chatzidoukas C., Processes, 12(12), 2770, 2024 (org/10.3390/pr12122770).
  5. “Foaming Properties of Chlorella sorokiniana Microalgal Biomass”, Georgiou D., Charisis A., Theocharidou A., Ritzoulis C., Papapanagiotou G., Samara C., Chatzidoukas C., Kalogianni E.P., Colloids Interfaces, 8(6), 66, 2024 (org/10.3390/colloids8060066).
  6. “Managing the interactions of illumination, nitrogen, and sodium bicarbonate for autotrophic biomass production and macromolecules accumulation in the microalga Chlorella sorokiniana”, Papapanagiotou G., Samara C., Chatzidoukas C., Algal Research, 80, 103550, 2024 (org/10.1016/j.algal.2024.103550).
  7. “Valorization of the Monoraphidium microalgal biomass for human nutrition applications”, Georgiou D., Exarhopoulos S., Charisis A., Simitsis S., Papapanagiotou G., Samara C., Katsiapi M., Kountrias G., Bouras S., Katsoulas N., Karapanagiotidis I.T., Chatzidoukas C., Kalogianni E.P., Journal of Applied Phycology, 36, 1293-1309, 2024 (doi.org/10.1007/s10811-024-03191-4).
  8. “Functional polysaccharide-coated SPIONs for in vitro mRNA delivery in breast cancer cells”, Tsave O., Psarrou M., Kastrinaki G., Papachristou E., Papi R., Zaspalis V., Nalbandian L., Sarafidis C., Choli-Papadopoulou T., Vamvakaki M., Chatzidoukas C., Adv., 5, 5410-5432, 2024 (doi.org/10.1039/D4MA00010B).
  9. “Study of Chlorella sorokiniana Cultivation in an Airlift Tubular Photobioreactor Using Anaerobic Digestate Substrate” Psachoulia P., Chatzidoukas C., Samaras P., Water, 16(3), 485, 2024 (org/10.3390/w16030485).
  10. “Comprehensive exploration of the growth and lipid synthesis phases of oleaginosus cultures implementing design of experiments and response surface methodology” Parisis V., Tsave O., Papanikolaou C., Pantazopoulou E., Chatzidoukas C., Bioengineering, 10(12), 1359, 2023 (doi.org/10.3390/bioengineering10121359).
  11. “Assessment of Nutrients Recovery Capacity and Biomass Growth of Four Microalgae Species in Anaerobic Digestion Effluent”, Psachoulia P., Schortsianiti S.-N., Lortou U., Gkelis S., Chatzidoukas C., Samaras P., Water, 14(2), 221, 2022 (org/10.3390/w14020221).
  12. “Enzymatic hydrolysis for the systematic production of second-generation glucose from the dual polysaccharide reserves of an anti-pollutant plant”, Migkos T.-M., Ioannidou G., Karapatsia A., Flevaris K., Chatzidoukas C., Bioresource Technology, 340, 125711, 2021 (org/10.1016/j.biortech.2021.125711).
  13. “Facilitating the industrial transition to microbial and microalgal factories through mechanistic modelling within the Industry 4.0 paradigm”, Flevaris K., Chatzidoukas C., Current Opinion in Chemical Engineering, 33, 100713, 2021 (org/10.1016/j.coche.2021.100713).
  14. “Optimal fed-batch bioreactor operating strategies for the microbial production of lignocellulosic bioethanol and exploration of their economic implications: A step forward towards sustainability and commercialization”, Flevaris K., Chatzidoukas C., Journal of Cleaner Production, 295, 126384, 2021 (org/10.1016/j.jclepro.2021.126384).
  15. “Illumination policies for Stichococcus cultures in an optimally operating lab-scale PBR toward the directed photosynthetic production of desired products”, Psachoulia P., Chatzidoukas C., Sustainability, 13(5), pp. 1–17, 2489, 2021 (doi.org/10.3390/su13052489).
  16. “Model-based dynamic optimization of the fermentative production of polyhydroxyalkanoates (PHAs) in fed-batch and sequence of continuously operating bioreactors”, Karasavvas E., Chatzidoukas C., Biochemical Engineering Journal, 162, 1077020, 2020 (org/10.1016/j.bej.2020.107702).
  17. “A Step Closer to the Market for Poly-hydroxy-alkanoates (PHAs) through their Bacterial Production in Continuous Bioreactors in Series: a Model Investigation of Novel Operating Strategies”, Karasavvas E., Chatzidoukas C., Computer Aided Chemical Engineering, 48, pp. 1687–1692, 2020 (org/10.1016/B978-0-12-823377-1.50282-2).

European or global research and innovation projects

  1. HORIZON-CL5-2024-D3-01 “Advanced Sustainable Biofuels Production from Purified Microalgae and Oleaginous Yeasts via Integrated Solar Hydrothermal Liquefaction – SUNFUSION” (Project Code: 101172945), 01/2025 – 12/2029.
  2. Greek Diaspora Fellowship Program – GDFP (Stavros Niarchos Foundation (SNF) & Institute of International Education (IIE)) “Collaborative Research in Algae for Production of Biofuels and Bioproducts”, 07/2020 – 09/2020.
  3. LIFE Climate Change Mitigation “LIFE Biomass C+ – Low-cost carbon positive bioethanol production with innovative Green Floating Filters in multiple water bodies” (Project Code: LIFE16 CCM/GR/000044), 09/2017 – 02/2021.